| Amniotic Membrane Treatments for Diabetic Neuropathy Wounds
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Amniotic Membrane Treatments for Diabetic Neuropathy Wounds

Amniotic Membrane Treatments for Diabetic Neuropathy Wounds

Treatment for Diabetic NeuropathyDiabetic neuropathy wounds are wound caused by neuropathy foot ulcers a condition resulting from peripheral neuropathy which affects diabetic patients. Diabetic neuropathy wounds heal slowly; this may further the infections on the patient. Prolonged wound healing time increases the possibility of hospitalization, and if the condition is not properly monitored, it can lead to amputation. Therefore, the primary objective of diabetic neuropathy wounds treatment is to ensure quick wound closure. To achieve the primary objective of diabetic neuropathy wounds treatment, routine wound treatments or conservative wound management are carried out. These include management of blood sugar levels, removal of dead tissues, prevention of new infections, off-loading, and hyperbaric oxygen therapy. However, despite the efforts put in to ensure rapid wound healing; most neuropathy wounds do not heal. It is important for a clinician to consider the use of advanced therapies if there are no signs of wound size reduction after four weeks of routine wound treatment.

To achieve the primary objective of diabetic neuropathy wounds treatment, routine wound treatments or conservative wound management are carried out. These include management of blood sugar levels, removal of dead tissues, prevention of new infections, off-loading, and hyperbaric oxygen therapy. However, despite the efforts put into ensure rapid wound healing; most neuropathy wounds do not heal. It is important for a clinician to consider the use of advanced therapies if there are no signs of wound size reduction after four weeks of routine wound treatment.

To achieve the primary objective of diabetic neuropathy wounds treatment, routine wound treatments or conservative wound management are carried out. These include management of blood sugar levels, removal of dead tissues, prevention of new infections, off-loading, and hyperbaric oxygen therapy. However, despite the efforts put into ensure rapid wound healing; most neuropathy wounds do not heal. It is important for a clinician to consider the use of advanced therapies if there are no signs of wound size reduction after four weeks of routine wound treatment.

One of advanced diabetic wound ulcers treatment is the use of the amniotic membrane. Amniotic membrane is a tissue with no vascular which is made up of the placenta. Amniotic membrane has shown treatment capability because it has characteristic of anti-inflammation; also it reserves many growth initiators which encourage tissue to grow and regenerate. These properties have enabled therapeutic to use an amniotic membrane to heal the wound, to repair and regenerate tissues.

Nowadays amniotic membranes can be accessed over the counter by a clinician for use in neuropathy wound treatment. The membranes are cryopreserved or dehydrated; they contain either amnion and chorion or amnion alone. Homograft of dehydrated human amnion/chorion membrane is made up of amnion and chorion layers of the amniotic membrane-derived from the human placenta. Research has indicated that dehydrated human amnion/chorion membrane encourages human dermal fibroblast reproduction that enhances wound healing because of growth initiators presence in the membrane.

It has been published on the successful results of dehydrated human amnion membrane to heal a plantar pedal burn; full healing was observed in the course of four weeks of single homograft application. Furthermore, a series of three stubborn diabetic neuropathy wounds cases that were taking too long to heal when applying the routine treatment underwent complete healing after dehydrated human amnion/chorion membrane treatment began.

On the other hand, cryopreserve placental membrane homograft is also effective in wound healing than standards or routine treatment procedures. Therefore, it can also be used for diabetic foot ulcer or wound treatment although it shows less consistency healing percentage compared to dehydrated human amnion/chorion membrane.

The clinician should use dehydrated human amnion/chorion membrane therapy because it results in quick healing when homograft application is made weekly. Therefore, this therapy is economical as the patients required fewer therapy center visits and wound dressing. Moreover, dehydrated human amnion/chorion membrane is a more clinically economical, efficient and effective treatment for diabetic neuropathy wounds compared to other advanced treatments like dermal graft. This is so because it has a high percentage and quick wound closure, a less number of homograft per wound healed, grafts are accessible in many sizes, and amnion membrane is simple to apply.

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